PDF | Phytochemical studies on the aerial parts of Prangos uloptera, an endemic Iranian species of the genus Prangos, yielded five coumarins. Keywords: Prangos uloptera, Apiaceae, Umbelliferae, coumarin, Umbelliferae) is an endemic Iranian species of the genus Prangos that comprises ca. Antimicrobial and antioxidant activities of coumarins from the roots of Ferulago campestris (Apiaceae). Basile A(1), Sorbo S, Spadaro V, Bruno.

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Coumarins from the aerial parts of Prangos uloptera Apiaceae.

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Londonderry, Northern Ireland, UK. Phytochemical studies on the aerial parts of Prangos ulopteraan endemic Iranian species of the genus Prangos coumarn, yielded five coumarins, xanthotoxin 1prangenin 2scopoletin 3deltoin 4 and prangolarin 5. The structures of these coumarins were elucidated by spectroscopic means, and the antioxidant potential of 1 – 5 was evaluated by the DPPH assay.

The chemotaxonomic significance of 1 – 5 is also discussed. Prangos ulopteraApiaceae, Umbelliferae, coumarin, furanocoumarin, marmesin, antioxidant, chemotaxonomy. Prangos ulopteraApiaceae, Umbelliferae, cumarina, furanocumarina, marmesina, antioxidante, quimiotaxonomia. Umbelliferae is an endemic Iranian species of the genus Prangos that comprises ca. Previous phytochemical investigations on the fruits and roots of P.

The essential oils obtained from the umbels of this species have recently been shown to contain various terpenoidal compounds Nazemieyh et al. As part of our on-going phytochemical and bioactivity studies on Iranian medicinal plants, we now report on the isolation, identification and antioxidant properties of five coumarins from the aerial parts of P.

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Mass accuracy was within 0. Chemical shifts d were in ppm. Precoated aluminium sheets silica gel 60 F 0. Silica 60G was used for vacuum liquid chromatography VLC. The aerial parts of Prangos uloptera DC.


A Voucher specimen No. The dried and ground aerial parts of P. The n -hexane extract 2 g was subjected to vacuum liquid chromatography VLC on silica gel, eluting with solvent mixtures of increasing polarity: The method ciumarin by Takao et al. It was allowed coymarin develop for 30 min.

The colour changes purple on white were noted. The UV absorbance was recorded at nm.

The experiment was performed in duplicate and the average absorption was noted for each concentration. Chromatographic analyses of the n coumafin extract of the aerial parts of P. Although coumarins have previously been reported from the roots and fruits of P. Also, except xanthotoxin 1 and prangenin 2none of these coumarins 3 – 5 fro ever apiacead reported from this plant. Xanthotoxin 1 and scopoletin 3 occur in many genera of the family Apiaceae as well as other families, e.

The genus Prangos is well-known for producing simple and furanocoumarins with various degrees of oxygenation and prenylations ISI Database, Within the genus Prangosprangenin 2 occurs in a number of species, including P. Ckumarin, apart from the genus Prangosprangenin 2 has also been reported from a few other genera, e. The occurrence of deltoin 4 within the genus Prangos is rather restricted mainly wpiaceae P. Peucedanum, Saposhnikovia, Seseli and Zosima.

Marmesin isovalerate prangolarin or oxypeucedanin, 5 occurs widely in the family Apiaceae, and also in the genera Atalantia, Citrus and Poncirus of the family Rutaceae Combined Chemical Dictionary, In the qualitative DPPH assay, except 3all compounds showed extremely low levels of antioxidant activity by displaying faint white spots against a purple background on the TLC plates. In the quantitative DPPH assay, scopoletin 3 was the most active among all compounds, and displayed a significant antioxidant activity with a RC 50 value of 2.

Coumarins and furocoumarins from fruits of Prangos uloptera. Khim Prir Soedin 6: Coumarins composition apuaceae Prangos uloptera roots. Khim Prir Soedin 1: Comparison of several Fang-Feng by coumarins, chromones and polyacetylenes.


THE APIACEAE FAMILY – Medicinal Plant Research Summary – Battle Ground Healing Arts

Chem Pharm Bull Coumarins from the roots of Prangos lamellate. Extractives of Angelica glauca. Screening seeds of some Scottish plants for free-radical scavenging activity.

Coumarins of the roots undergrounds and fruits of Prangos equisetoides. Psoralen and other linear furanocoumarins as phytoalexins in Glehnia littoralis.

Essential oil of Prangos uloptera DC. J Essent Oil Res Coumarins from the aerial part of Halocnemum strobilaceum. Essential oil composition of the umbels and fruits of Prangos uloptera DC. Nat Prod Commun 2: Chemical composition of the oil of Prangos uloptera DC.

Coumarins from umbels of Prangos pabularia Lind. J Indian Chem Soc Coumarins and gamma-pyrone derivatives from Prangos pabularia: A simple screening method for antioxidants and isolation of several antioxidants produced by marine bacteria from fish and shellfish. Biosci Biotech Bioch Preparative isolation of imperatorin, oxypeucedanin and isoimperatorin from apiaeae Chinese herb “bai couamrin Angelica dahurica Fisch ex Hoffm Benth. J Chromatogr A Terpenoids and gamma pyrone derivatives from Prangos teshiganica.

All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. Plant material The aerial parts of Prangos uloptera DC. Preparation of plant extracts The dried and ground aerial parts of P. Isolation and identification of compounds The n -hexane extract 2 g was subjected to vacuum liquid chromatography VLC on silica gel, eluting with solvent mixtures of increasing polarity: Lothario Meissner, – Jd.

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